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Base64 is a group of similar binary-to-text encoding schemes that represent binary data in an ASCII string format by translating it into a radix-64 representation. The term Base64 originates from a specific MIME content transfer encoding.
Each base64 digit represents exactly 6 bits of data. The particular set of 64 characters chosen to represent the 64 place-values for the base varies between implementations. The general strategy is to choose 64 characters that are both members of a subset common to most encodings, and also printable. This combination leaves the data unlikely to be modified in transit through information systems, such as email, that were traditionally not 8-bit clean. For example, MIME's Base64 implementation uses A–Z, a–z, and 0–9 for the first 62 values. Other variations share this property but differ in the symbols chosen for the last two values; an example is UTF-7.
The earliest instances of this type of encoding were created for dialup communication between systems running the same OS — e.g., uuencode for UNIX, BinHex for the TRS-80 (later adapted for the Macintosh) — and could therefore make more assumptions about what characters were safe to use. For instance, uuencode uses uppercase letters, digits, and many punctuation characters, but no lowercase.